In the main window of the program, click PC Tuneup.
In the Boot Manager section, click Open Boot Manager.
Select the program that you want to enable/disable
and click the link next to the 
icon.
Certain programs and applications are configured to run automatically when your PC starts up. However, sometimes there are so many startup programs that they may slow down your computer and even pose a security risk.
Your Panda product allows you to manage the way your computer starts with a simple, easy-to-use Boot Manager. The Boot Manager displays a list of all the startup programs installed on your computer, allowing you to prevent them from running and even delete the registry key that launches them.
To do that, follow these steps:
In the main window of the program, click PC Tuneup.
In the Boot Manager section, click Open Boot Manager.
Select the program that you want to enable/disable
and click the link next to the icon.
To delete the registry key that launches the selected program, click the Delete link next to the registry key displayed.